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Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis

Mitogen-activated protein kinase (MAPK) phosphatase 5 (MKP-5) is a member of the dual-specificity family of protein tyrosine phosphatases that negatively regulates p38 MAPK and the JNK. MKP-5-deficient mice exhibit improved muscle repair and reduced fibrosis in an animal model of muscular dystrophy....

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Xylourgidis, Nikos, Min, Kisuk, Ahangari, Farida, Yu, Guoying, Herazo-Maya, Jose D., Karampitsakos, Theodoros, Aidinis, Vassilis, Binzenhöfer, Leonhard, Bouros, Demosthenes, Bennett, Anton M., Kaminski, Naftali, Tzouvelekis, Argyrios
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879900/
https://ncbi.nlm.nih.gov/pubmed/31483681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00264.2018
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