SH2 Domain–Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis

Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic fatal lung disease with dismal prognosis and no cure. The potential role of the ubiquitously expressed SH2 domain–containing tyrosine phosphatase-2 (SHP2) as a therapeutic target has not been studied in IPF. Objectives: To determine the exp...

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Publicado no:Am J Respir Crit Care Med
Main Authors: Tzouvelekis, Argyrios, Yu, Guoying, Lino Cardenas, Christian L., Herazo-Maya, Jose D., Wang, Rong, Woolard, Tony, Zhang, Yi, Sakamoto, Koji, Lee, Hojin, Yi, Jae-Sung, DeIuliis, Giuseppe, Xylourgidis, Nikolaos, Ahangari, Farida, Lee, Patty J., Aidinis, Vassilis, Herzog, Erica L., Homer, Robert, Bennett, Anton M., Kaminski, Naftali
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378419/
https://ncbi.nlm.nih.gov/pubmed/27736153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201602-0329OC
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