MAP Kinase Phosphatase-2 Plays a Critical Role in Response to Infection by Leishmania mexicana

In this study we generated a novel dual specific phosphatase 4 (DUSP4) deletion mouse using a targeted deletion strategy in order to examine the role of MAP kinase phosphatase-2 (MKP-2) in immune responses. Lipopolysaccharide (LPS) induced a rapid, time and concentration-dependent increase in MKP-2...

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Detalhes bibliográficos
Main Authors: Al-Mutairi, Mashael S., Cadalbert, Laurence C., McGachy, H. Adrienne, Shweash, Muhannad, Schroeder, Juliane, Kurnik, Magdalena, Sloss, Callum M., Bryant, Clare E., Alexander, James, Plevin, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978729/
https://ncbi.nlm.nih.gov/pubmed/21085614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001192
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