MAP Kinase Phosphatase-2 Plays a Key Role in the Control of Infection with Toxoplasma gondii by Modulating iNOS and Arginase-1 Activities in Mice

The dual specific phosphatase, MAP kinase phosphatase-2 (MKP-2) has recently been demonstrated to negatively regulate macrophage arginase-1 expression, while at the same time to positively regulate iNOS expression. Consequently, MKP-2 is likely to play a significant role in the host interplay with i...

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Detalles Bibliográficos
Main Authors: Woods, Stuart, Schroeder, Juliane, McGachy, Helen A., Plevin, Robin, Roberts, Craig W., Alexander, James
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744406/
https://ncbi.nlm.nih.gov/pubmed/23966857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003535
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