Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression

The effects of Leishmania mexicana metacyclic promastigotes upon MAP kinase signalling in mouse bone marrow macrophages and subsequent expression of the disease regulatory proteins iNOS and COX-2 were studied. At a ratio of 5:1, promastigotes caused a marked increase in phosphorylation of the three...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shweash, Muhannad, Adrienne McGachy, H., Schroeder, Juliane, Neamatallah, Thikryat, Bryant, Clare E., Millington, Owain, Mottram, Jeremy C., Alexander, James, Plevin, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173610/
https://ncbi.nlm.nih.gov/pubmed/21664694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.05.013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados