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Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

Mitochondrial DNA (mtDNA) heteroplasmy (intra-individual variation) varies among different human tissues and increases with age, suggesting that the majority of mtDNA heteroplasmies are acquired, rather than inherited. However, the extent to which heteroplasmic sites are shared across a tissue remai...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hübner, Alexander, Wachsmuth, Manja, Schröder, Roland, Li, Mingkun, Eis-Hübinger, Anna Maria, Madea, Burkhard, Stoneking, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677727/
https://ncbi.nlm.nih.gov/pubmed/31375696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47570-1
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