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Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

Mitochondrial DNA (mtDNA) heteroplasmy (intra-individual variation) varies among different human tissues and increases with age, suggesting that the majority of mtDNA heteroplasmies are acquired, rather than inherited. However, the extent to which heteroplasmic sites are shared across a tissue remai...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Hübner, Alexander, Wachsmuth, Manja, Schröder, Roland, Li, Mingkun, Eis-Hübinger, Anna Maria, Madea, Burkhard, Stoneking, Mark
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677727/
https://ncbi.nlm.nih.gov/pubmed/31375696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47570-1
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