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Inactivation of Nell-1 in chondrocytes significantly impedes appendicular skeletogenesis

NELL-1, an osteoinductive protein, has been shown to regulate skeletal ossification. Interestingly, an interstitial 11p14.1-p15.3 deletion involving the Nell-1 gene was recently reported in a patient with short stature and delayed fontanelle closure. Here we sought to define the role of Nell-1 in en...

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Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Qi, Huichuan, Kim, Jong Kil, Ha, Pin, Chen, Xiaoyan, Chen, Eric, Chen, Yao, Li, Jiayi, Pan, Hsin Chuan, Yu, Mengliu, Mohazeb, Yasamin, Azer, Sophia, Baik, Lloyd, Kwak, Jin Hee, Ting, Kang, Zhang, Xinli, Hu, Min, Soo, Chia
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677149/
https://ncbi.nlm.nih.gov/pubmed/30352124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3615
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