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Inactivation of Nell-1 in chondrocytes significantly impedes appendicular skeletogenesis
NELL-1, an osteoinductive protein, has been shown to regulate skeletal ossification. Interestingly, an interstitial 11p14.1-p15.3 deletion involving the Nell-1 gene was recently reported in a patient with short stature and delayed fontanelle closure. Here we sought to define the role of Nell-1 in en...
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| Udgivet i: | J Bone Miner Res |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6677149/ https://ncbi.nlm.nih.gov/pubmed/30352124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3615 |
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