Inactivation of Nell-1 in chondrocytes significantly impedes appendicular skeletogenesis

NELL-1, an osteoinductive protein, has been shown to regulate skeletal ossification. Interestingly, an interstitial 11p14.1-p15.3 deletion involving the Nell-1 gene was recently reported in a patient with short stature and delayed fontanelle closure. Here we sought to define the role of Nell-1 in en...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Qi, Huichuan, Kim, Jong Kil, Ha, Pin, Chen, Xiaoyan, Chen, Eric, Chen, Yao, Li, Jiayi, Pan, Hsin Chuan, Yu, Mengliu, Mohazeb, Yasamin, Azer, Sophia, Baik, Lloyd, Kwak, Jin Hee, Ting, Kang, Zhang, Xinli, Hu, Min, Soo, Chia
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677149/
https://ncbi.nlm.nih.gov/pubmed/30352124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3615
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