Inactivation of Nell-1 in chondrocytes significantly impedes appendicular skeletogenesis

NELL-1, an osteoinductive protein, has been shown to regulate skeletal ossification. Interestingly, an interstitial 11p14.1-p15.3 deletion involving the Nell-1 gene was recently reported in a patient with short stature and delayed fontanelle closure. Here we sought to define the role of Nell-1 in en...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Bone Miner Res
Egile Nagusiak: Qi, Huichuan, Kim, Jong Kil, Ha, Pin, Chen, Xiaoyan, Chen, Eric, Chen, Yao, Li, Jiayi, Pan, Hsin Chuan, Yu, Mengliu, Mohazeb, Yasamin, Azer, Sophia, Baik, Lloyd, Kwak, Jin Hee, Ting, Kang, Zhang, Xinli, Hu, Min, Soo, Chia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677149/
https://ncbi.nlm.nih.gov/pubmed/30352124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3615
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