Inactivation of Nell-1 in chondrocytes significantly impedes appendicular skeletogenesis

NELL-1, an osteoinductive protein, has been shown to regulate skeletal ossification. Interestingly, an interstitial 11p14.1-p15.3 deletion involving the Nell-1 gene was recently reported in a patient with short stature and delayed fontanelle closure. Here we sought to define the role of Nell-1 in en...

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Publicado en:J Bone Miner Res
Autores principales: Qi, Huichuan, Kim, Jong Kil, Ha, Pin, Chen, Xiaoyan, Chen, Eric, Chen, Yao, Li, Jiayi, Pan, Hsin Chuan, Yu, Mengliu, Mohazeb, Yasamin, Azer, Sophia, Baik, Lloyd, Kwak, Jin Hee, Ting, Kang, Zhang, Xinli, Hu, Min, Soo, Chia
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677149/
https://ncbi.nlm.nih.gov/pubmed/30352124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3615
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