Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway

Isl1 expression marks progenitor populations in developing embryos. In this study, we investigated the contribution of Isl1-expressing cells that utilize the β-catenin pathway to skeletal development. Inactivation of β-catenin in Isl1-expressing cells caused agenesis of the hindlimb skeleton and abs...

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Main Authors: Akiyama, Ryutaro, Kawakami, Hiroko, Taketo, M. Mark, Evans, Sylvia M., Wada, Naoyuki, Petryk, Anna, Kawakami, Yasuhiko
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947553/
https://ncbi.nlm.nih.gov/pubmed/24424161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.01.001
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