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Rapamycin enhanced the antitumor effects of doxorubicin in myelogenous leukemia K562 cells by downregulating the mTOR/p70S6K pathway

Chronic myelogenous leukemia (CML) is a common hematological malignancy. Some patients progressing to the blast phase develop chemotherapeutic drug resistance. In the authors' previous study, it was found that the mammalian target of rapamycin (mTOR) pathway was activated in CML and that rapamy...

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Bibliografski detalji
Izdano u:Oncol Lett
Glavni autori: Li, Jie, Liu, Wenjing, Hao, Hongling, Wang, Qiuyi, Xue, Liying
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676723/
https://ncbi.nlm.nih.gov/pubmed/31404320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10589
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