Dual PI3K/mTOR inhibitor NVP-BEZ235 decreases the proliferation of doxorubicin-resistant K562 cells

Acute myelogenous leukemia (AML) is frequently accompanied by a poor prognosis. The majority of patients with AML will experience recurrence due to multiple drug resistance. Our previous study reported that targeting the mTOR pathway may increase cell sensitivity to doxorubicin (Doxo) and provide an...

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Udgivet i:Mol Med Rep
Main Authors: Li, Jie, Wang, Xiaozi, Ma, Chuanbao, Xu, Shasha, Xu, Mengyao, Yang, Jie, Wang, Ruicang, Xue, Liying
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930928/
https://ncbi.nlm.nih.gov/pubmed/34223631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11940
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