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Effects of Neddylation and mTOR Inhibition in Acute Myelogenous Leukemia

Acute myelogenous leukemia (AML) is a heterogeneous disease and often relapses after standard chemotherapy. Recently, the neddylation (NEDD8) and the mammalian target of rapamycin (mTOR) signaling pathways have emerged as promising pharmaceutical targets for AML therapy. However, the interaction of...

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Bibliografische gegevens
Gepubliceerd in:Transl Oncol
Hoofdauteurs: Guo, Naxin, Azadniv, Mitra, Coppage, Myra, Nemer, Mary, Mendler, Jason, Becker, Michael, Liesveld, Jane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348338/
https://ncbi.nlm.nih.gov/pubmed/30699367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.01.001
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