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Effects of Neddylation and mTOR Inhibition in Acute Myelogenous Leukemia

Acute myelogenous leukemia (AML) is a heterogeneous disease and often relapses after standard chemotherapy. Recently, the neddylation (NEDD8) and the mammalian target of rapamycin (mTOR) signaling pathways have emerged as promising pharmaceutical targets for AML therapy. However, the interaction of...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Guo, Naxin, Azadniv, Mitra, Coppage, Myra, Nemer, Mary, Mendler, Jason, Becker, Michael, Liesveld, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348338/
https://ncbi.nlm.nih.gov/pubmed/30699367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.01.001
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