Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support

Bone marrow mesenchymal stromal cells (MSCs) constitute one of the important components of the hematopoietic microenvironmental niche. In vivo studies have shown that depletion of marrow MSCs resulted in reduction of hematopoietic stem cell content, and there is in vitro evidence that marrow MSCs ar...

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Publicado en:Leukemia
Autores principales: Azadniv, Mitra, Myers, Jason R., McMurray, Helene R., Guo, Naxin, Rock, Phil, Coppage, Myra L., Ashton, John, Becker, Michael W., Calvi, Laura M., Liesveld, Jane L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214245/
https://ncbi.nlm.nih.gov/pubmed/31492897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0568-8
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