Evolution of acute myelogenous leukemia stem cell properties after treatment and progression

Most cancers evolve over time as patients initially responsive to therapy acquire resistance to the same drugs at relapse. Cancer stem cells have been postulated to represent a therapy-refractory reservoir for relapse, but formal proof of this model is lacking. We prospectively characterized leukemi...

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Publicado en:Blood
Main Authors: Ho, Tzu-Chieh, LaMere, Mark, Stevens, Brett M., Ashton, John M., Myers, Jason R., O’Dwyer, Kristen M., Liesveld, Jane L., Mendler, Jason H., Guzman, Monica, Morrissette, Jennifer D., Zhao, Jianhua, Wang, Eunice S., Wetzler, Meir, Jordan, Craig T., Becker, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Plenary Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043124/
https://ncbi.nlm.nih.gov/pubmed/27421961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-02-695312
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