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Effects of Neddylation and mTOR Inhibition in Acute Myelogenous Leukemia

Acute myelogenous leukemia (AML) is a heterogeneous disease and often relapses after standard chemotherapy. Recently, the neddylation (NEDD8) and the mammalian target of rapamycin (mTOR) signaling pathways have emerged as promising pharmaceutical targets for AML therapy. However, the interaction of...

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Foilsithe in:Transl Oncol
Main Authors: Guo, Naxin, Azadniv, Mitra, Coppage, Myra, Nemer, Mary, Mendler, Jason, Becker, Michael, Liesveld, Jane
Formáid: Artigo
Teanga:Inglês
Foilsithe: Neoplasia Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348338/
https://ncbi.nlm.nih.gov/pubmed/30699367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.01.001
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