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Rapamycin enhanced the antitumor effects of doxorubicin in myelogenous leukemia K562 cells by downregulating the mTOR/p70S6K pathway

Chronic myelogenous leukemia (CML) is a common hematological malignancy. Some patients progressing to the blast phase develop chemotherapeutic drug resistance. In the authors' previous study, it was found that the mammalian target of rapamycin (mTOR) pathway was activated in CML and that rapamy...

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Bibliografiset tiedot
Julkaisussa:Oncol Lett
Päätekijät: Li, Jie, Liu, Wenjing, Hao, Hongling, Wang, Qiuyi, Xue, Liying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2019
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676723/
https://ncbi.nlm.nih.gov/pubmed/31404320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10589
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