Modeling RNA-binding protein specificity in vivo by precisely registering protein-RNA crosslink sites

RNA-binding proteins (RBPs) regulate post-transcriptional gene expression by recognizing short and degenerate sequence motifs in their target transcripts, but precisely defining their binding specificity remains challenging. Crosslinking and immunoprecipitation (CLIP) allows for mapping of the exact...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Feng, Huijuan, Bao, Suying, Rahman, Mohammad Alinoor, Weyn-Vanhentenryck, Sebastien M., Khan, Aziz, Wong, Justin, Shah, Ankeeta, Flynn, Elise D., Krainer, Adrian R., Zhang, Chaolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676488/
https://ncbi.nlm.nih.gov/pubmed/31226278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados