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The immunostimulatory effects and pro‐apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll‐like receptor 4

BACKGROUND: Recombinant human calcineurin B subunit (rhCNB) has been shown to be an immune‐stimulatory protein promoting cytokine production and inducing phenotypic maturation of Dendritic cells (DCs). In vivo, it has good antitumor efficacy, and has potential as an antitumor drug. Exogenous rhCNB w...

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Podrobná bibliografie
Vydáno v:Cancer Med
Hlavní autoři: Yang, Jinju, Zhang, Hongwei, Zhu, Ziwei, Gao, Yadan, Xiang, Benqiong, Wei, Qun
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675711/
https://ncbi.nlm.nih.gov/pubmed/31218844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2158
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