The immunostimulatory effects and pro‐apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll‐like receptor 4

BACKGROUND: Recombinant human calcineurin B subunit (rhCNB) has been shown to be an immune‐stimulatory protein promoting cytokine production and inducing phenotypic maturation of Dendritic cells (DCs). In vivo, it has good antitumor efficacy, and has potential as an antitumor drug. Exogenous rhCNB w...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Yang, Jinju, Zhang, Hongwei, Zhu, Ziwei, Gao, Yadan, Xiang, Benqiong, Wei, Qun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675711/
https://ncbi.nlm.nih.gov/pubmed/31218844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2158
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