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The immunostimulatory effects and pro‐apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll‐like receptor 4

BACKGROUND: Recombinant human calcineurin B subunit (rhCNB) has been shown to be an immune‐stimulatory protein promoting cytokine production and inducing phenotypic maturation of Dendritic cells (DCs). In vivo, it has good antitumor efficacy, and has potential as an antitumor drug. Exogenous rhCNB w...

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Détails bibliographiques
Publié dans:Cancer Med
Auteurs principaux: Yang, Jinju, Zhang, Hongwei, Zhu, Ziwei, Gao, Yadan, Xiang, Benqiong, Wei, Qun
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675711/
https://ncbi.nlm.nih.gov/pubmed/31218844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2158
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