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The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumor cells
The calcineurin B subunit (CNB) has antitumor activity. We showed previously that recombinant human CNB (rhCNB) also had strong anti-tumor activity in vivo, and was thus a promising candidate anti-tumor drug. It appeared to kill tumor cells via immunomodulation. Here, we show that rhCNB inhibits the...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5630379/ https://ncbi.nlm.nih.gov/pubmed/29029479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19507 |
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