The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumor cells

The calcineurin B subunit (CNB) has antitumor activity. We showed previously that recombinant human CNB (rhCNB) also had strong anti-tumor activity in vivo, and was thus a promising candidate anti-tumor drug. It appeared to kill tumor cells via immunomodulation. Here, we show that rhCNB inhibits the...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Yang, Yang, Yang, Huan, Yang, Jinju, Li, Li, Xiang, Benqiong, Wei, Qun
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630379/
https://ncbi.nlm.nih.gov/pubmed/29029479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19507
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