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Accumulation of Amyloid Precursor Protein in the Mitochondrial Import Channels of Human Alzheimer’s Disease Brain Is Associated with Mitochondrial Dysfunction

Mitochondrial dysfunction is one of the major intracellular lesions of Alzheimer’s disease (AD). However, the causative factors involved in the mitochondrial dysfunction in human AD are not well understood. Here we report that nonglycosylated full-length and C-terminal truncated amyloid precursor pr...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Devi, Latha, Prabhu, Badanavalu M., Galati, Domenico F., Avadhani, Narayan G., Anandatheerthavarada, Hindupur K.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675337/
https://ncbi.nlm.nih.gov/pubmed/16943564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1469-06.2006
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