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Mutant huntingtin Impairs the Post-Golgi Trafficking of Brain-Derived Neurotrophic Factor But Not Its Val66Met Polymorphism

Brain-derived neurotrophic factor (BDNF) polymorphism is associated with the pathophysiology of several neurodegenerative disorders, including Huntington's disease. In view of these data and the involvement of huntingtin in intracellular trafficking, we examined the intracellular transport and...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: del Toro, Daniel, Canals, Josep M., Ginés, Silvia, Kojima, Masami, Egea, Gustavo, Alberch, Jordi
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674849/
https://ncbi.nlm.nih.gov/pubmed/17151278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3873-06.2006
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