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Mutant huntingtin Impairs the Post-Golgi Trafficking of Brain-Derived Neurotrophic Factor But Not Its Val66Met Polymorphism

Brain-derived neurotrophic factor (BDNF) polymorphism is associated with the pathophysiology of several neurodegenerative disorders, including Huntington's disease. In view of these data and the involvement of huntingtin in intracellular trafficking, we examined the intracellular transport and...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: del Toro, Daniel, Canals, Josep M., Ginés, Silvia, Kojima, Masami, Egea, Gustavo, Alberch, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674849/
https://ncbi.nlm.nih.gov/pubmed/17151278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3873-06.2006
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