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Mutant huntingtin Impairs the Post-Golgi Trafficking of Brain-Derived Neurotrophic Factor But Not Its Val66Met Polymorphism

Brain-derived neurotrophic factor (BDNF) polymorphism is associated with the pathophysiology of several neurodegenerative disorders, including Huntington's disease. In view of these data and the involvement of huntingtin in intracellular trafficking, we examined the intracellular transport and...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: del Toro, Daniel, Canals, Josep M., Ginés, Silvia, Kojima, Masami, Egea, Gustavo, Alberch, Jordi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674849/
https://ncbi.nlm.nih.gov/pubmed/17151278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3873-06.2006
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