Calpain-Cleaved Collapsin Response Mediator Protein-3 Induces Neuronal Death after Glutamate Toxicity and Cerebral Ischemia

Collapsin response mediator proteins (CRMPs) mediate growth cone collapse during development, but their roles in adult brains are not clear. Here we report the findings that the full-length CRMP-3 (p63) is a direct target of calpain that cleaves CRMP-3 at the N terminus (+76 amino acid). Interesting...

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Publicado en:J Neurosci
Autores principales: Hou, Sheng T., Jiang, Susan X., Desbois, Angele, Huang, Deqi, Kelly, John, Tessier, Luc, Karchewski, Laurie, Kappler, Joachim
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2006
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674801/
https://ncbi.nlm.nih.gov/pubmed/16495451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4485-05.2006
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