Calpain-Cleaved Collapsin Response Mediator Protein-3 Induces Neuronal Death after Glutamate Toxicity and Cerebral Ischemia

Collapsin response mediator proteins (CRMPs) mediate growth cone collapse during development, but their roles in adult brains are not clear. Here we report the findings that the full-length CRMP-3 (p63) is a direct target of calpain that cleaves CRMP-3 at the N terminus (+76 amino acid). Interesting...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hou, Sheng T., Jiang, Susan X., Desbois, Angele, Huang, Deqi, Kelly, John, Tessier, Luc, Karchewski, Laurie, Kappler, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674801/
https://ncbi.nlm.nih.gov/pubmed/16495451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4485-05.2006
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