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Calpain-1 Cleaves and Activates Caspase-7

Caspase-7 is an executioner caspase that plays a key role in apoptosis, cancer, and a number of neurodegenerative diseases. The mechanism of caspase-7 activation by granzyme B and caspase-3 has been well characterized. However, whether other proteases such as calpains activate or inactivate caspase-...

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Détails bibliographiques
Auteurs principaux: Gafni, Juliette, Cong, Xin, Chen, Sylvia F., Gibson, Bradford W., Ellerby, Lisa M.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757245/
https://ncbi.nlm.nih.gov/pubmed/19617626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038174
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