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Calpain cleaves methionine aminopeptidase-2 in a rat model of ischemia/reperfusion

Ischemic stroke results in multiple injurious signals within a cell including dysregulation of calcium homeostasis. Consequently, there is an increase in the enzymatic activity of the calpains, calcium dependent proteases that are thought to contribute to neuronal injury. In addition, cellular stres...

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Библиографические подробности
Главные авторы: Clinkinbeard, Tiffanie, Ghoshal, Sarbani, Craddock, Susan, Pettigrew, L. Creed, Guttmann, Rodney P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570617/
https://ncbi.nlm.nih.gov/pubmed/23295187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.12.039
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