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Calpain cleaves methionine aminopeptidase-2 in a rat model of ischemia/reperfusion

Ischemic stroke results in multiple injurious signals within a cell including dysregulation of calcium homeostasis. Consequently, there is an increase in the enzymatic activity of the calpains, calcium dependent proteases that are thought to contribute to neuronal injury. In addition, cellular stres...

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Detalhes bibliográficos
Main Authors: Clinkinbeard, Tiffanie, Ghoshal, Sarbani, Craddock, Susan, Pettigrew, L. Creed, Guttmann, Rodney P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570617/
https://ncbi.nlm.nih.gov/pubmed/23295187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.12.039
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