Early and Rapid Engraftment of Bone Marrow-Derived Microglia in Scrapie

Prion neuroinvasion is accompanied by maximal activation of microglia, the significance of which for pathogenesis is unknown. Here, we used bone marrow (BM) cells expressing GFP (green fluorescent protein) to study the turnover of microglia in mouse scrapie. We found that ≥50% of all brain microglia...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Priller, Josef, Prinz, Marco, Heikenwalder, Mathias, Zeller, Nicolas, Schwarz, Petra, Heppner, Frank L., Aguzzi, Adriano
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2006
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674798/
https://ncbi.nlm.nih.gov/pubmed/17093096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2275-06.2006
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