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Early and Rapid Engraftment of Bone Marrow-Derived Microglia in Scrapie

Prion neuroinvasion is accompanied by maximal activation of microglia, the significance of which for pathogenesis is unknown. Here, we used bone marrow (BM) cells expressing GFP (green fluorescent protein) to study the turnover of microglia in mouse scrapie. We found that ≥50% of all brain microglia...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Priller, Josef, Prinz, Marco, Heikenwalder, Mathias, Zeller, Nicolas, Schwarz, Petra, Heppner, Frank L., Aguzzi, Adriano
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674798/
https://ncbi.nlm.nih.gov/pubmed/17093096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2275-06.2006
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