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Prion pathogenesis in the absence of Toll-like receptor signalling
To reach the brain from peripheral sites, prions must colonize various cell types within the lymphoreticular compartment. However, no prion entry receptors are yet known. Toll-like receptors (TLRs) are pattern-recognition receptors that bind a multitude of pathogens and are therefore candidates as e...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315829/ https://ncbi.nlm.nih.gov/pubmed/12612611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor731 |
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