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Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells

Variant Creutzfeldt–Jakob disease and scrapie are typically initiated by extracerebral exposure to prions, and exhibit early prion accumulation in germinal centers. Follicular dendritic cells (FDCs), whose development and maintenance in germinal centers depends on tumor necrosis factor (TNF) and lym...

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Bibliographic Details
Main Authors: Prinz, Marco, Montrasio, Fabio, Klein, Michael A., Schwarz, Petra, Priller, Josef, Odermatt, Bernhard, Pfeffer, Klaus, Aguzzi, Adriano
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC117406/
https://ncbi.nlm.nih.gov/pubmed/11792852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022626399
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