Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells

Variant Creutzfeldt–Jakob disease and scrapie are typically initiated by extracerebral exposure to prions, and exhibit early prion accumulation in germinal centers. Follicular dendritic cells (FDCs), whose development and maintenance in germinal centers depends on tumor necrosis factor (TNF) and lym...

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Detalles Bibliográficos
Main Authors: Prinz, Marco, Montrasio, Fabio, Klein, Michael A., Schwarz, Petra, Priller, Josef, Odermatt, Bernhard, Pfeffer, Klaus, Aguzzi, Adriano
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC117406/
https://ncbi.nlm.nih.gov/pubmed/11792852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022626399
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