Nigrostriatal Dopaminergic Neurodegeneration in the Weaver Mouse Is Mediated via Neuroinflammation and Alleviated by Minocycline Administration

The murine mutant weaver (gene symbol, wv) mouse, which carries a mutation in the gene encoding the G-protein inwardly rectifying potassium channel Girk2, exhibits a diverse range of defects as a result of postnatal cell death in several different brain neuron subtypes. Loss of dopaminergic nigrostr...

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Publicat a:J Neurosci
Autors principals: Peng, Jun, Xie, Lin, Stevenson, Fang Feng, Melov, Simon, Di Monte, Donato A., Andersen, Julie K.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2006
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674792/
https://ncbi.nlm.nih.gov/pubmed/17093086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3447-06.2006
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