Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration

Minocycline is a broad-spectrum tetracycline antibiotic. A number of preclinical studies have shown that minocycline exhibits neuroprotective effects in various animal models of neurological diseases. However, it remained unknown whether minocycline is effective to prevent neuron loss. To systematic...

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Publicado en:Sci Rep
Autores principales: Cheng, Shanshan, Hou, Jinxing, Zhang, Chen, Xu, Congyu, Wang, Long, Zou, Xiaoxia, Yu, Huahong, Shi, Yun, Yin, Zhenyu, Chen, Guiquan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441131/
https://ncbi.nlm.nih.gov/pubmed/26000566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10535
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