Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration

Minocycline is a broad-spectrum tetracycline antibiotic. A number of preclinical studies have shown that minocycline exhibits neuroprotective effects in various animal models of neurological diseases. However, it remained unknown whether minocycline is effective to prevent neuron loss. To systematic...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Cheng, Shanshan, Hou, Jinxing, Zhang, Chen, Xu, Congyu, Wang, Long, Zou, Xiaoxia, Yu, Huahong, Shi, Yun, Yin, Zhenyu, Chen, Guiquan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441131/
https://ncbi.nlm.nih.gov/pubmed/26000566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10535
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