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Impaired Inactivation Gate Stabilization Predicts Increased Persistent Current for an Epilepsy-Associated SCN1A Mutation
Mutations in SCN1A (encoding the neuronal voltage-gated sodium channel α(1) subunit, Na(V)1.1, or SCN1A) are associated with genetic epilepsy syndromes including generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epilepsy of infancy. Here, we present the formulation and use...
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| Publicado no: | J Neurosci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674674/ https://ncbi.nlm.nih.gov/pubmed/17065438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3378-06.2006 |
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