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The Transcriptional Activator Hypoxia Inducible Factor 2 (HIF-2/EPAS-1) Regulates the Oxygen-Dependent Expression of Erythropoietin in Cortical Astrocytes

In the ischemic or hypoxic brain, astrocytes appear to be one of the main sources of erythropoietin (EPO). In this study, we investigated the differential contribution of hypoxia inducible factor (HIF) isoforms to the regulation of hypoxic EPO expression in cultured astrocytes. In addition, using an...

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Pubblicato in:J Neurosci
Autori principali: Chavez, Juan C., Baranova, Oxana, Lin, Janice, Pichiule, Paola
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674587/
https://ncbi.nlm.nih.gov/pubmed/16971531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2838-06.2006
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