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Erythropoietin inhibits HIF-1α expression via upregulation of PHD-2 transcription and translation in an in-vitro model of hypoxia ischemia

Hypoxia inducible factor (HIF)-1α is the central transcriptional factor for the regulation of oxygen-associated genes in response to hypoxia. Erythropoietin (EPO), a hematopoietic growth factor, increases oxygen availability during hypoxia/ischemia and is associated with neuroprotection following hy...

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Bibliografiska uppgifter
Huvudupphovsmän: Souvenir, Rhonda, Flores, Jerry J., Ostrowski, Robert P., Manaenko, Anatol, Duris, Kamil, Tang, Jiping
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946340/
https://ncbi.nlm.nih.gov/pubmed/24323731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-013-0312-z
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