Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2

Death-associated protein 5 (DAP5) is an atypical isoform of the translation initiation scaffolds eukaryotic initiation factor 4GI (eIF4GI) and eIF4GII (eIF4GI/II), which recruit mRNAs to ribosomes in mammals. Unlike eIF4GI/II, DAP5 binds eIF2β, a subunit of the eIF2 complex that delivers methionyl-t...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Bryant, Jeffrey D., Brown, Michael C., Dobrikov, Mikhail I., Dobrikova, Elena Y., Gemberling, Sarah L., Zhang, Qing, Gromeier, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954183/
https://ncbi.nlm.nih.gov/pubmed/29530922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00647-17
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