Long-Term Depression of NMDA Receptor-Mediated Synaptic Transmission Is Dependent on Activation of Metabotropic Glutamate Receptors and Is Altered to Long-Term Potentiation by Low Intracellular Calcium Buffering

Synaptic plasticity of NMDA receptor (NMDAR)-mediated transmission was investigated in the rat dentate gyrus in vitro. Isolated NMDAR EPSCs were recorded from granule cells of the dentate gyrus in response to stimulation of the medial perforant path. Long-term potentiation (LTP) or long-term depress...

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Vydáno v:J Neurosci
Hlavní autoři: Harney, Sarah C., Rowan, Michael, Anwyl, Roger
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2006
Témata:
Brief Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674584/
https://ncbi.nlm.nih.gov/pubmed/16436598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2753-05.2006
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