Long-Term Depression of NMDA Receptor-Mediated Synaptic Transmission Is Dependent on Activation of Metabotropic Glutamate Receptors and Is Altered to Long-Term Potentiation by Low Intracellular Calcium Buffering

Synaptic plasticity of NMDA receptor (NMDAR)-mediated transmission was investigated in the rat dentate gyrus in vitro. Isolated NMDAR EPSCs were recorded from granule cells of the dentate gyrus in response to stimulation of the medial perforant path. Long-term potentiation (LTP) or long-term depress...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Harney, Sarah C., Rowan, Michael, Anwyl, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674584/
https://ncbi.nlm.nih.gov/pubmed/16436598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2753-05.2006
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