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Long-Term Depression of NMDA Receptor-Mediated Synaptic Transmission Is Dependent on Activation of Metabotropic Glutamate Receptors and Is Altered to Long-Term Potentiation by Low Intracellular Calcium Buffering

Synaptic plasticity of NMDA receptor (NMDAR)-mediated transmission was investigated in the rat dentate gyrus in vitro. Isolated NMDAR EPSCs were recorded from granule cells of the dentate gyrus in response to stimulation of the medial perforant path. Long-term potentiation (LTP) or long-term depress...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Harney, Sarah C., Rowan, Michael, Anwyl, Roger
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674584/
https://ncbi.nlm.nih.gov/pubmed/16436598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2753-05.2006
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