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Myelin Impairs CNS Remyelination by Inhibiting Oligodendrocyte Precursor Cell Differentiation

Demyelination in the adult CNS can be followed by extensive repair. However, in multiple sclerosis, the differentiation of oligodendrocyte lineage cells present in demyelinated lesions is often inhibited by unknown factors. In this study, we test whether myelin debris, a feature of demyelinated lesi...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Kotter, Mark R., Li, Wen-Wu, Zhao, Chao, Franklin, Robin J. M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674302/
https://ncbi.nlm.nih.gov/pubmed/16399703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2615-05.2006
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