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Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination

The increasing effectiveness of new disease-modifying drugs that suppress disease activity in multiple sclerosis has opened up opportunities for regenerative medicines that enhance remyelination and potentially slow disease progression. Although several new targets for therapeutic enhancement of rem...

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Autores principales: Syed, Yasir A, Baer, Alexandra, Hofer, Matthias P, González, Ginez A, Rundle, Jon, Myrta, Szymon, Huang, Jeffrey K, Zhao, Chao, Rossner, Moritz J, Trotter, Matthew W B, Lubec, Gert, Franklin, Robin J M, Kotter, Mark R
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914530/
https://ncbi.nlm.nih.gov/pubmed/24293318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201303123
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