Parkinson's Disease Brain Mitochondrial Complex I Has Oxidatively Damaged Subunits and Is Functionally Impaired and Misassembled

Loss of mitochondrial complex I catalytic activity in the electron transport chain (ETC) is found in multiple tissues from individuals with sporadic Parkinson's disease (PD) and is a property of some PD model neurotoxins. Using special ETC subunit-specific and complex I immunocapture antibodies...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Keeney, Paula M., Xie, Jing, Capaldi, Roderick A., Bennett, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674236/
https://ncbi.nlm.nih.gov/pubmed/16687518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0984-06.2006
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