A carregar...
Deletion of Presenilin 1 Hydrophilic Loop Sequence Leads to Impaired γ-Secretase Activity and Exacerbated Amyloid Pathology
γ-Secretase processing of the amyloid precursor protein (APP) generates Aβ(40) and Aβ(42), peptides that constitute the principal components of the β-amyloid plaque pathology of Alzheimer's disease (AD). The γ-secretase activity is executed by a high-molecular-weight complex of which presenilin...
Na minha lista:
| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2006
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674120/ https://ncbi.nlm.nih.gov/pubmed/16597739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5384-05.2006 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|