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Motoneurons Derived from Embryonic Stem Cells Express Transcription Factors and Develop Phenotypes Characteristic of Medial Motor Column Neurons

Embryonic stem (ES) cells differentiate into functional motoneurons when treated with a sonic hedgehog (Shh) agonist and retinoic acid (RA). Whether ES cells can be directed to differentiate into specific subtypes of motoneurons is unknown. We treated embryoid bodies generated from HBG3 ES cells wit...

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Vydáno v:J Neurosci
Hlavní autoři: Soundararajan, Prabakaran, Miles, Gareth B., Rubin, Lee L., Brownstone, Robert M., Rafuse, Victor F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674087/
https://ncbi.nlm.nih.gov/pubmed/16554476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5537-05.2006
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